Collagen scaffolds produced by Matricel are being used by various research groups. The following references either describe aspects of the methods to produce these scaffolds or their use in different fields of application.  

References 

 

Becker, C., Olde-Damink, L., Laeufer, T., Brehmer, B., Heschel, I., Jakse, G.: 'UroMaix' scaffolds: novel collagen matrices for application in tissue engineering of the urinary tract, Int. J. Artif. Organs 29, 764-771 (2006).

Bozkurt, A., Brook, G., Moeller, S., Lassner, F., Sellhaus, B., Weis, J.Woeltje, M., Tank, J., Beckmann, Ch., Fuchs, P., Olde Damink, L., Schügner, F., Heschel, I., Pallua, N.: In Vitro Assessment of Axonal Growth Using Dorsal Root Ganglia Explants in a Novel Three-Dimensional Collagen Matrix, Tissue Eng. 13, 2971-2979 (2007).

Brehmer, B., Rohrmann, D., Rau, G., Jakse, G.: Bladder wall replacement by tissue engineering and autologous keratinocytes in minipigs, BJU Int. 97, 829-836 (2006).

Brehmer, B., Rohrmann, D., Becker, C., Rau, G., Jakse, G.: Different types of scaffolds for reconstruction of the urinary tract by tissue engineering, Urol. Int. 78: 23-29 (2007).

Heschel, I., Schoof, H., Kuberka, M., v. Heimburg, D., Noah, E. M., Brehmer, B., Rau, G.: Production of collagen sponges by directional solidification and subsequent freeze-drying for applications in tissue engineering, Cryobiology 41, 328 (2000).

Jäger, M., Degistirici, Ö., Knipper, A., Fischer, J., Sager, M., Krauspe, R.: Bone Healing and Migration of Cord Blood Derived Stem Cells Into a Critical Size Femoral Defect After Xenotransplantation, J. Bone Miner. Res. 22, 12241233 (2007).

Kuberka, M., von Heimburg, D., Schoof, H., Heschel, I., Rau, G.: Magnification of the pore size in biodegradable collagen sponges, Int J Artif Organs 25, 67-73 (2002).

Kroehne, V., Heschel, I., Schügner, F., Lasrich, D., Bartsch, J.W., Jockusch, H.: Use of a novel collagen matrix with oriented pore structure for muscle cell differentiation in cell culture and in grafts, J. Cell. Mol. Med. 12 (2008)

Olde Damink, L.H.H., P.J. Dijkstra, M.J.A. van Luyn, P.B. van Wachem, P. Nieuwenhuis, J. Feijen: Crosslinking of dermal sheep collagen using a water-soluble carbodiimide, Biomaterials 17, 765-773 (1996).

Olde Damink, L.H.H., P.J. Dijkstra, M.J.A. van Luyn, P.B. van Wachem, P. Nieuwenhuis, J. Feijen: In vitro degradation of dermal sheep collagen crosslinked using a water-soluble carbodiimide, Biomaterials 17, 679-684 (1996).

Schoof, H., Apel, J., Heschel, I., Rau, G.: Control of pore structure and size in freeze-dried collagen sponges, J. Biomed. Mater. Res. 58: 352-357 (2001).

Schoof, H., Bruns, L., Fischer, A., Heschel, I., Rau, G.: Dendritic ice morphology in unidirectionally solidified collagen suspensions, J. Crystal Growth 209, 122-129 (2000).

van Wachem, P.B., M.J.A. van Luyn, L.H.H. Olde Damink, P.J. Dijkstra, J. Feijen, P. Nieuwenhuis: Biocompatibility and tissue regenerating capacity of crosslinked dermal sheep collagen, J. Biomedical Materials Research 28, 353-363 (1994).

von Heimburg D, Zachariah S, Heschel I, Kühling H, Schoof H, Hafemann B, Pallua N: Human preadipocytes seeded on freeze-dried collagen scaffolds investigated in vitro and in vivo, Biomaterials 22, 429-438 (2001).

Willers, C., Chen, J., Wood, D., Xu, J., Zheng. M.H.: Autologous Chondrocyte Implantation with Collagen Bioscaffold for the Treatment of Osteochondral Defects in Rabbits, Tissue Engineering 11, 1065-1076 (2005).

Zheng, M.H., Willers, C., Kirilak, L., Yates, P., Xu, J., Wood, D., Shimmin, A.: Matrix-induced autologous chondrocyte implantation (MACI): biological and histological assessment. Tissue Eng. 13, 737-746 (2007).